Annotation Detail
Information
- Associated Genes
- TLR7
- Associated Variants
-
TLR7 p.Gln11Pro (p.Q11P)
(
ENST00000380659.4 )
TLR7 p.Gln11Leu (p.Q11L) ( ENST00000380659.4 )
TLR7 p.Gln11Pro (p.Q11P) ( ENST00000380659.4 )
TLR7 p.Gln11Leu (p.Q11L) ( ENST00000380659.4 ) - Associated Disease
- IMMUNE SUPPRESSION
- Source Database
- DisGeNET
- Description
- Presence of the most frequent TLR7 polymorphism, TLR7 Gln11Leu, was associated with higher viral loads and accelerated progression to advanced immune suppression in HIV patients.
- Pubmed
- 19114863
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs