Annotation Detail

Information
Associated Genes
CHEK2
Associated Variants
CHEK2 p.Ile200Thr (p.I200T) ( ENST00000348295.7, ENST00000382580.6, ENST00000402731.6, ENST00000403642.5, ENST00000404276.6, ENST00000405598.5, ENST00000425190.7, ENST00000649563.1, ENST00000650281.1 )
CHEK2 p.Ile200Thr (p.I200T) ( ENST00000348295.7, ENST00000382580.6, ENST00000402731.6, ENST00000403642.5, ENST00000404276.6, ENST00000405598.5, ENST00000425190.7, ENST00000649563.1, ENST00000650281.1 )
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
Pubmed
24880342
Original source reporting the Gene Disease association
GWASCAT
DisGENET score for the Gene Disease association
0.129815514656609
Year of publication
2014
Drugs