Annotation Detail

Information
Associated Genes
CRP
Associated Variants
FTO c.46-23525T>A ( ENST00000636491.1, ENST00000636218.1, ENST00000471389.6, ENST00000637969.1, ENST00000637001.1 )
rs17782313
rs3091244
rs3091244
NC_000002.12:g.634905T>C
FTO c.46-23525T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
rs17782313
rs3091244
rs3091244
NC_000002.12:g.634905T>C
Associated Disease
obesity
Source Database
DisGeNET
Description
Using the three obesity-associated polymorphisms FTO rs9939609, MC4R rs17782313, and TMEM18 rs6548238, and the CRP promoter polymorphism rs3091244 in instrumental variable analyses, we estimated the associations between genetically increased BMI and telomere length and between genetically increased C-reactive protein and telomere length.
Pubmed
24762112
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.15095564307047
Year of publication
2015
Drugs