Annotation Detail

Information
Associated Genes
TMEM18
Associated Variants
FTO c.46-23525T>A ( ENST00000636491.1, ENST00000636218.1, ENST00000471389.6, ENST00000637969.1, ENST00000637001.1 )
rs17782313
NC_000002.12:g.634905T>C
ADRB2 p.Thr164Ile (p.T164I) ( ENST00000305988.6 )
FTO c.46-23525T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
rs17782313
NC_000002.12:g.634905T>C
ADRB2 p.Thr164Ile (p.T164I) ( ENST00000305988.6 )
Associated Disease
diabetes mellitus
Source Database
DisGeNET
Description
We tested the hypothesis that the ADRB2rs1800888(Thr164Ile) polymorphism associates with risk of obesity and diabetes and compared effect sizes with those of FTO(rs9939609), MC4R(rs17782313), and TMEM18(rs6548238).
Pubmed
22466342
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2012
Drugs