Annotation Detail

Information
Associated Genes
IRS1
Associated Variants
IRS1 MUTATION
IRS1 MUTATION
rs2943634
IRS1 SNV
rs2943634
IRS1 SNV
Associated Disease
Metabolic syndrome X
Source Database
DisGeNET
Description
In this study we found support for the hypothesis that weight regulation and insulin metabolism are involved in MetS development.MC4R rs17782312 and IRS1 rs2943634 may explain part of the genetic variation in MetS.
Pubmed
23101478
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0871770408059268
Year of publication
2012
Drugs