Annotation Detail
Information
- Associated Genes
- TRIM69
- Associated Variants
-
CHUK p.Val268Ile (p.V268I)
(
ENST00000370397.8 )
RAG1 c.-289+1666G>A ( ENST00000697714.1, ENST00000697713.1, ENST00000697715.1 )
rs4807000
IL1RL1 c.-149-1132G>A ( ENST00000233954.6, ENST00000404917.6 )
rs2569191
rs2915863
rs2569192
CHUK p.Val268Ile (p.V268I) ( ENST00000370397.8 )
RAG1 c.-289+1666G>A ( ENST00000697713.1, ENST00000697714.1, ENST00000697715.1 )
rs4807000
IL1RL1 c.-149-1132G>A ( ENST00000233954.6, ENST00000404917.6 )
rs2569191
rs2915863
rs2569192 - Associated Disease
- Wheezing
- Source Database
- DisGeNET
- Description
- Of the remaining 15 SNPs, for seven we found significant relationships between genotype and endotoxin exposure in the genetic association study in relation to symptomatic airway hyper-responsiveness (CD14-rs2915863 and rs2569191, TRIF-rs4807000), current wheeze (ST-2-rs17639215, IKK-1-rs2230804, and TRIF-rs4807000), and atopy (CD14-rs2915863 and rs2569192, TRAF-6-rs5030411, and IKK-1-rs2230804).
- Pubmed
- 25102764
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs