Annotation Detail

Information
Associated Genes
CYP3A5
Associated Variants
KLK3 p.Ile179Thr (p.I179T) ( ENST00000326003.7, ENST00000360617.7, ENST00000593997.5, ENST00000595952.5, ENST00000597483.5 )
KLK3 p.Ile179Thr (p.I179T) ( ENST00000326003.7, ENST00000360617.7, ENST00000593997.5, ENST00000595952.5, ENST00000597483.5 )
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Patients with CYP3A5*3/*3 and KLK3 I179T CC/TC genotypes had increased OR 2.30, 95% CI 1.16-4.58 for metastatic disease.
Pubmed
18306354
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2008
Drugs