Annotation Detail
Information
- Associated Genes
- CTLA4
- Associated Variants
-
rs180088
NC_000002.12:g.203867624C>T ( ENST00000696479.1 )
C5 p.Val808Ile (p.V808I) ( ENST00000223642.3, ENST00000696281.1 )
rs180088
NC_000002.12:g.203867624C>T ( ENST00000696479.1 )
C5 p.Val808Ile (p.V808I) ( ENST00000223642.3, ENST00000696281.1 )
CTLA4 UNKNOWN
CTLA4 UNKNOWN - Associated Disease
- Metabolic syndrome X
- Source Database
- DisGeNET
- Description
- In a marker-by-marker analysis, the ADRB2 rs180088 (OR 1.22, 95% CI 1.01-1.48) and PAI1 rs1799768 (OR 1.05, 95% CI 1.01-1.10) were associated with an increased MetS risk, whereas the C5 rs17611 (OR 0.95, 95% CI 0.91-1.00) and the CTLA4 rs5742909 (OR 0.91, 95% CI 0.84-0.99) were associated with a decreased risk.
- Pubmed
- 19619703
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs