Annotation Detail

Information
Associated Genes
MMP9
Associated Variants
MMP9 p.Gln279Arg (p.Q279R) ( ENST00000372330.3 )
MMP9 p.Arg574Pro (p.R574P) ( ENST00000372330.3 )
MMP9 p.Arg574Leu (p.R574L) ( ENST00000372330.3 )
MMP9 p.Arg668Gln (p.R668Q) ( ENST00000372330.3 )
MMP9 p.Arg668Pro (p.R668P) ( ENST00000372330.3 )
MMP9 p.Gln279Arg (p.Q279R) ( ENST00000372330.3 )
MMP9 p.Arg574Pro (p.R574P) ( ENST00000372330.3 )
MMP9 p.Arg574Leu (p.R574L) ( ENST00000372330.3 )
MMP9 p.Arg668Gln (p.R668Q) ( ENST00000372330.3 )
MMP9 p.Arg668Pro (p.R668P) ( ENST00000372330.3 )
Associated Disease
coronary artery disease
Source Database
DisGeNET
Description
These findings suggest that MMP-9 R279Q, P574R and R668Q may have combined effect in the occurrence of CAD and -1562 CT/TT genotypes may contribute to CAD in diabetics and MI in CAD patients.
Pubmed
19283512
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0295186076648864
Year of publication
2010
Drugs