Annotation Detail

Information
Associated Genes
IRF5
Associated Variants
TNPO3 SNV
TNPO3 SNV
Associated Disease
systemic scleroderma
Source Database
DisGeNET
Description
[Additionally, we confirm and firmly establish the role of the MHC (P = 2.31 x 10(-18)), IRF5 (P = 1.86 x 10(-13)) and STAT4 (P = 3.37 x 10(-9)) gene regions as SSc genetic risk factors.]
Pubmed
20383147
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.143093760301806
Year of publication
2010
Drugs