Annotation Detail
Information
- Associated Genes
- IL1F10
- Associated Variants
-
IL1A c.*561T>C
(
ENST00000263339.4 )
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
IL1A c.96+116G>A ( ENST00000263339.4 )
IL1A c.*561T>C ( ENST00000263339.4 )
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
IL1A c.96+116G>A ( ENST00000263339.4 ) - Associated Disease
- ankylosing spondylitis
- Source Database
- DisGeNET
- Description
- In addition to the three known IL-1 polymorphisms, rs2856836, rs17561, and rs1894399, found in previous meta-analysis, this meta-analysis shows that the IL-1F10.3 and IL-1A+889 polymorphisms are associated with the development of AS in Europeans but not in Asians.
- Pubmed
- 21962386
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.007915421552047
- Year of publication
- 2012
Drugs