Annotation Detail
Information
- Associated Genes
- G3BP2
- Associated Variants
-
G3BP2 MUTATION
G3BP2 MUTATION - Associated Disease
- Neoplasm Metastasis
- Source Database
- DisGeNET
- Description
- Our findings reveal a TWIST1-G3BP2 mechanotransduction pathway that responds to biomechanical signals from the tumour microenvironment to drive EMT, invasion and metastasis.
- Pubmed
- 25893917
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs