Annotation Detail

Information
Associated Genes
MMP12
Associated Variants
MMP12 MUTATION
MMP12 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
The possibility to exploit tumor homing and activity of autologous MMP12-engineered ECFCs represents a novel way to combat melanoma by a personalized therapy, without rejection risk.The i.v. injection of radiolabelled MMP12-ECFCs can thus provide a new theranostic approach to control melanoma progression and metastasis.
Pubmed
25003596
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs