Annotation Detail

Information
Associated Genes
UCN3
Associated Variants
UCN3 MUTATION
UCN3 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
The effect of demethylation agent in SPC can be reversed by β-catenin depletion but not E-cadherin depletion which indicated that the methylation mediated β-catenin silencing might enhance NSCLC invasion and metastasis in an E-cadherin independent manner.
Pubmed
25396757
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs