Annotation Detail

Information
Associated Genes
MMP1
Associated Variants
MMP1 MUTATION
MMP1 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Resistant cells expressed higher levels of genes coding for cancer stem cell markers (JARID1B, CD271 and Fibronectin) as well as genes involved in drug resistance (ABCG2), cell invasion and promotion of metastasis (MMP-1 and MMP-2).
Pubmed
25725450
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.147173981773023
Drugs