Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET c.73+9277T>C ( ENST00000355710.8, ENST00000684216.2, ENST00000615310.5, ENST00000683278.2, ENST00000640619.2, ENST00000340058.6, ENST00000638465.2, ENST00000713926.1 )
RET p.Ser32Leu (p.S32L) ( ENST00000638465.2, ENST00000683278.2, ENST00000640619.2, ENST00000340058.6, ENST00000713926.1, ENST00000355710.8, ENST00000684216.2, ENST00000615310.5 )
RET p.Ala45= (p.A45=) ( ENST00000684216.2, ENST00000355710.8, ENST00000713926.1, ENST00000640619.2, ENST00000683278.2, ENST00000340058.6, ENST00000638465.2, ENST00000615310.5 )
RET p.Pro64Leu (p.P64L) ( ENST00000684216.2, ENST00000615310.5, ENST00000355710.8, ENST00000713926.1, ENST00000638465.2, ENST00000683278.2, ENST00000640619.2, ENST00000340058.6 )
RET p.Glu136Lys (p.E136K) ( ENST00000340058.6, ENST00000640619.2, ENST00000638465.2, ENST00000713926.1, ENST00000683278.2, ENST00000355710.8, ENST00000615310.5, ENST00000684216.2 )
RET p.Glu136Ter (p.E136*) ( ENST00000355710.8, ENST00000684216.2, ENST00000615310.5, ENST00000640619.2, ENST00000683278.2, ENST00000340058.6, ENST00000638465.2, ENST00000713926.1 )
RET p.Arg180Ter (p.R180*) ( ENST00000638465.2, ENST00000340058.6, ENST00000683278.2, ENST00000640619.2, ENST00000713926.1, ENST00000355710.8, ENST00000684216.2, ENST00000615310.5 )
RET p.Arg231His (p.R231H) ( ENST00000713926.1, ENST00000340058.6, ENST00000615310.5, ENST00000355710.8 )
RET p.Arg313Gln (p.R313Q) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Arg330Gln (p.R330Q) ( ENST00000713926.1, ENST00000355710.8, ENST00000615310.5, ENST00000340058.6 )
RET p.Phe393Leu (p.F393L) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET c.1880-2A>G ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Ile647= (p.I647=) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Ser765Pro (p.S765P) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Arg897Gln (p.R897Q) ( ENST00000340058.6, ENST00000713926.1, ENST00000355710.8, ENST00000615310.5 )
RET p.Arg972Gly (p.R972G) ( ENST00000713926.1, ENST00000615310.5, ENST00000355710.8, ENST00000340058.6 )
RET p.Arg982Cys (p.R982C) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET c.73+9277T>C ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000638465.2, ENST00000640619.2, ENST00000683278.2, ENST00000684216.2, ENST00000713926.1 )
RET p.Ser32Leu (p.S32L) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000638465.2, ENST00000640619.2, ENST00000683278.2, ENST00000684216.2, ENST00000713926.1 )
RET p.Ala45= (p.A45=) ( ENST00000713926.1, ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000638465.2, ENST00000640619.2, ENST00000683278.2, ENST00000684216.2 )
RET p.Pro64Leu (p.P64L) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000638465.2, ENST00000640619.2, ENST00000683278.2, ENST00000684216.2, ENST00000713926.1 )
RET p.Glu136Lys (p.E136K) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000638465.2, ENST00000640619.2, ENST00000683278.2, ENST00000684216.2, ENST00000713926.1 )
RET p.Glu136Ter (p.E136*) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000638465.2, ENST00000640619.2, ENST00000683278.2, ENST00000684216.2, ENST00000713926.1 )
RET p.Arg180Ter (p.R180*) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000638465.2, ENST00000640619.2, ENST00000683278.2, ENST00000684216.2, ENST00000713926.1 )
RET p.Arg231His (p.R231H) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Arg313Gln (p.R313Q) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Arg330Gln (p.R330Q) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Phe393Leu (p.F393L) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET c.1880-2A>G ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Ile647= (p.I647=) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Ser765Pro (p.S765P) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Arg897Gln (p.R897Q) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Arg972Gly (p.R972G) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Arg982Cys (p.R982C) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
Associated Disease
Hirschsprung disease 1
Source Database
DisGeNET
Description
NA
Original source reporting the Gene Disease association
CLINVAR
DisGENET score for the Gene Disease association
0.15610176898668
Year of publication
NA
Drugs