Annotation Detail

Information
Associated Genes
RHOA
Associated Variants
RHOA MUTATION
RHOA MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Here we show that RHOA inactivation contributes to colorectal cancer progression/metastasis, largely through the activation of Wnt/β-catenin signalling.
Pubmed
25413277
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00953026008780303
Drugs