Annotation Detail

Information
Associated Genes
SPINK1
Associated Variants
SPINK1 p.Asn34Ser (p.N34S) ( ENST00000510027.2, ENST00000296695.10 )
SPINK1 p.Asn34Ser (p.N34S) ( ENST00000296695.10, ENST00000510027.2 )
Associated Disease
Pancreatitis, Chronic
Source Database
DisGeNET
Description
Two common haplotypes, c.101A>G (p.N34S) and c.-215G>A, and four intronic alterations of the serine protease inhibitor Kazal type 1 (SPINK1) gene have been found to increase the risk for CP in the Asia Pacific region.
Pubmed
21323990
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.220099677972261
Year of publication
2011
Drugs