Annotation Detail

Information
Associated Genes
DKK3
Associated Variants
DKK2 p.Arg146Leu (p.R146L) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
DKK2 p.Arg146Gln (p.R146Q) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
DKK2 p.Arg146Leu (p.R146L) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
DKK2 p.Arg146Gln (p.R146Q) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
Associated Disease
renal cell carcinoma
Source Database
DisGeNET
Description
To the authors' knowledge, this is the first report documenting that DKK3 polymorphisms are associated with RCC and that the DKK2 rs17037102 polymorphism may be a predictor for survival in patients with RCC after radical nephrectomy.
Pubmed
19562778
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00318135759484294
Year of publication
2009
Drugs