Annotation Detail

Information
Associated Genes
NTRK2
Associated Variants
NTRK2 MUTATION
NTRK2 MUTATION
Associated Disease
myocardial infarction
Source Database
DisGeNET
Description
BDNF/TrkB alleviated cardiac ischemic injury and inhibited cardiomyocytes apoptosis by regulating TRPC3/6 channels, which provides a novel potential therapeutic candidate for MI.
Pubmed
25892961
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
16
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs