Annotation Detail
Information
- Associated Genes
- IL13
- Associated Variants
-
IL4R c.770+744G>A
(
ENST00000543915.6,
ENST00000395762.7,
ENST00000170630.6 )
CSF2RB p.Pro702Ser (p.P702S) ( ENST00000403662.8, ENST00000406230.5 )
IL13 c.-93+487C>T
IL4R c.770+744G>A ( ENST00000170630.6, ENST00000395762.7, ENST00000543915.6 )
CSF2RB p.Pro702Ser (p.P702S) ( ENST00000403662.8, ENST00000406230.5 )
IL13 c.-93+487C>T - Associated Disease
- Hay fever
- Source Database
- DisGeNET
- Description
- Of 60 tagging single-nucleotide polymorphisms covering eight genes (CSF2, IL3, IL4, IL13, CSF2RB, IL4R, IL13RA1, IL13RA2), several were related to pollen allergies among controls: IL4R rs3024647 (dominant OR: 1.5; 95% CI: 1.0-2.3; P = 0.04), CSF2RB rs16997517 (dominant OR: 2.2; 95% CI: 1.0-4.7; P = 0.04), and IL13 rs1800925 (per-allele OR: 1.7; 95% CI: 1.3-2.4; P = 0.0007).
- Pubmed
- 21071541
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0076439796799667
- Year of publication
- 2011
Drugs