Annotation Detail
Information
- Associated Genes
- BCR
- Associated Variants
-
BCR MUTATION
BCR MUTATION - Associated Disease
- Myeloproliferative disease
- Source Database
- DisGeNET
- Description
- Current data suggest that constitutively active JAK-STAT signaling plays a central role in the pathogenesis of BCR-ABL1-negative myeloproliferative neoplasms (MPNs), regardless of the specific underlying molecular abnormality.
- Pubmed
- 25520049
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,CTD_human,LHGDN
- DisGENET score for the Gene Disease association
- 0.128153187684073
Drugs