Annotation Detail

Information
Associated Genes
CHRNA5
Associated Variants
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
Associated Disease
nicotine dependence
Source Database
DisGeNET
Description
Peer smoking had a substantially lower effect on nicotine dependence among those with the high-risk AA genotype at the functional SNP rs16969968 (CHRNA5) than among those with lower-risk genotypes.
Pubmed
20840187
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0196633669216207
Year of publication
2010
Drugs