Annotation Detail

Information
Associated Genes
CHRNA5
Associated Variants
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
Associated Disease
nicotine dependence
Source Database
DisGeNET
Description
Minor allele carriers at rs16969968 in the nicotinic acetylcholine receptor α5 subunit gene (CHRNA5) have been shown to exhibit both reduced cognitive control and greater nicotine dependence.
Pubmed
24934182
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0196633669216207
Year of publication
2014
Drugs