Annotation Detail

Information
Associated Genes
GSTP1
Associated Variants
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
Associated Disease
breast carcinoma
Source Database
DisGeNET
Description
When COMT(LL) was combined with either glutathione S-transferase (GST) M1 null or with GSTP1 Ile-105-Val/Val-105-Val (intermediate/low activity, respectively) genotypes, the risk for developing postmenopausal breast cancer was also significantly increased.
Pubmed
9407957
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0192723729177015
Year of publication
1997
Drugs