Annotation Detail
Information
- Associated Genes
- CRYGD
- Associated Variants
-
GSTP1 c.232+13C>A
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
GSTP1 c.337-322G>A
GSTP1 S185=
GSTP1 c.232+13C>A
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
GSTP1 c.337-322G>A
GSTP1 S185= - Associated Disease
- Carcinoma of lung
- Source Database
- DisGeNET
- Description
- When Phase 2 software was used to reconstruct the haplotype for GSTP1, the haplotype CACA (rs749174+rs1695 + rs762803+rs4891) exhibited an increased risk of lung cancer among smokers (adjust odds ratio 1.53; 95%CI 1.04-2.25, P=0.033).
- Pubmed
- 24786234
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2014
Drugs