Annotation Detail
Information
- Associated Genes
- CSF3
- Associated Variants
-
CSF3 MUTATION
CSF3 MUTATION - Associated Disease
- multiple sclerosis
- Source Database
- DisGeNET
- Description
- In conclusion, our data strongly indicate that G-CSF-induced CXCR2 expression is regulated in a CerS2-dependent manner and that CerS2 thereby promotes the migration of neutrophils, thus, contributing to inflammation and the development of EAE and MS.
- Pubmed
- 25697397
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs