Annotation Detail

Information
Associated Genes
HLA-DQA2
Associated Variants
HLA-DQA2 MUTATION
HLA-DQA2 MUTATION
Associated Disease
multiple sclerosis
Source Database
DisGeNET
Description
This study, which shows for the first time a functional HLA-DQA1/DRB1 mixed isotype heterodimer and its potential association with disease susceptibility, provides a rationale for a potential effect on MS risk from DQA1*01:02 through functional DQA1*01:02;DRB1*15:01 antigen presentation.
Pubmed
25911099
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs