Annotation Detail
Information
- Associated Genes
- IGF1
- Associated Variants
-
IGF1 MUTATION
IGF1 MUTATION - Associated Disease
- multiple myeloma
- Source Database
- DisGeNET
- Description
- Furthermore, exposure of AZD8055-treated cells to IGF1 induced p-Akt S(473) and rescued multiple myeloma cells from apoptosis despite mTOR kinase inhibition and TORC2/Akt blockage.
- Pubmed
- 25172964
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0132445699051424
Drugs