Annotation Detail

Information
Associated Genes
HNF4A
Associated Variants
VPS26A c.*449C>T ( ENST00000263559.11, ENST00000395098.5, ENST00000373382.5 )
HMG20A c.-4-3556A>G ( ENST00000381714.7, ENST00000336216.9 )
AP3S2 c.*4490G>T ( ENST00000336418.9 )
rs4812829 ( ENST00000316673.9, ENST00000457232.5, ENST00000609795.5 )
rs3923113
ST6GAL1 c.-324-15112C>T ( ENST00000169298.8, ENST00000457772.6, ENST00000677292.1 )
rs5945326
VPS26A c.*449C>T ( ENST00000263559.11, ENST00000373382.5, ENST00000395098.5 )
HMG20A c.-4-3556A>G ( ENST00000336216.9, ENST00000381714.7 )
AP3S2 c.*4490G>T ( ENST00000336418.9 )
rs4812829 ( ENST00000316673.9, ENST00000457232.5, ENST00000609795.5 )
rs3923113
ST6GAL1 c.-324-15112C>T ( ENST00000169298.8, ENST00000457772.6, ENST00000677292.1 )
rs5945326
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
We genotyped 11,319 Japanese participants (8,318 with type 2 diabetes and 3,001 controls) for each of the 7 SNPs-rs5945326 near DUSP9, rs3923113 near GRB14, rs16861329 in ST6GAL1, rs1802295 in VPS26A, rs7178572 in HMG20A, rs2028299 near AP3S2, and rs4812829 in HNF4A-and examined the association of each of these 7 SNPs with type 2 diabetes by using logistic regression analysis.
Pubmed
23029454
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.60754205370071
Year of publication
2012
Drugs