Annotation Detail
Information
- Associated Genes
- HTR1A
- Associated Variants
-
SLC6A4 c.1651-1436G>A
(
ENST00000650711.1,
ENST00000401766.6,
ENST00000261707.7 )
HTR1A c.*287T>C ( ENST00000323865.5 )
HTR5A c.742-1251C>T ( ENST00000287907.3 )
SLC6A4 c.1651-1436G>A ( ENST00000261707.7, ENST00000401766.6, ENST00000650711.1 )
HTR1A c.*287T>C ( ENST00000323865.5 )
HTR5A c.742-1251C>T ( ENST00000287907.3 ) - Associated Disease
- Mood Disorders
- Source Database
- DisGeNET
- Description
- Three genes contributed exclusively to mood disorders, one through a main effect (HTR5A (rs1657268)) and two through gene-environment interactions with CPA (HTR1A (rs878567) and SLC6A4 (rs3794808)).
- Pubmed
- 19381154
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0177071919902662
- Year of publication
- 2010
Drugs