Annotation Detail
Information
- Associated Genes
- CYBA
- Associated Variants
-
rs1580833
CYBA c.58+290C>T ( ENST00000696163.1, ENST00000696160.1, ENST00000567174.5, ENST00000696159.1, ENST00000696161.1, ENST00000696157.1, ENST00000696162.1, ENST00000569359.5, ENST00000696158.1, ENST00000261623.8, ENST00000696156.1 )
TXN2 c.387+2309A>G ( ENST00000216185.7, ENST00000403313.5, ENST00000416967.1 )
TXN2 c.387+30A>C ( ENST00000216185.7, ENST00000403313.5, ENST00000416967.1 )
rs4821494
rs2301241
rs1580833
CYBA c.58+290C>T ( ENST00000261623.8, ENST00000567174.5, ENST00000569359.5, ENST00000696156.1, ENST00000696157.1, ENST00000696158.1, ENST00000696159.1, ENST00000696160.1, ENST00000696161.1, ENST00000696162.1, ENST00000696163.1 )
TXN2 c.387+2309A>G ( ENST00000216185.7, ENST00000403313.5, ENST00000416967.1 )
TXN2 c.387+30A>C ( ENST00000216185.7, ENST00000403313.5, ENST00000416967.1 )
rs4821494
rs2301241 - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- Six polymorphisms evaluated in the combined set showed significantly modified breast cancer risk per allele in the joint analysis, including SNPs in CYBA (encoding a subunit of the NADPH oxidase: rs3794624), MT2A (metallothionein 2A: rs1580833), TXN (thioredoxin: rs2301241), and in TXN2 (thioredoxin 2: rs2267337, rs2281082, rs4821494).
- Pubmed
- 21792883
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2011
Drugs