Annotation Detail

Information
Associated Genes
SLCO6A1
Associated Variants
GSTO1 p.Ala140Asp (p.A140D) ( ENST00000369713.10, ENST00000539281.5, ENST00000369710.8 )
GSTO2 p.Asn142Asp (p.N142D) ( ENST00000450629.6, ENST00000338595.7, ENST00000369707.2 )
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
rs3957357
GSTO1 p.Ala140Asp (p.A140D) ( ENST00000369710.8, ENST00000369713.10, ENST00000539281.5 )
GSTO2 p.Asn142Asp (p.N142D) ( ENST00000338595.7, ENST00000369707.2, ENST00000450629.6 )
GSTP1 c.[313A>G;341=] ( ENST00000398606.10 )
rs3957357
Associated Disease
Carcinoma of bladder
Source Database
DisGeNET
Description
To examine the association of six glutathione transferase (GST) gene polymorphisms (GSTT1, GSTP1/rs1695, GSTO1/rs4925, GSTO2/rs156697, GSTM1, GSTA1/rs3957357) with the survival of patients with muscle invasive bladder cancer and the genotype modifying effect on chemotherapy.
Pubmed
24040330
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00434306995328485
Year of publication
2013
Drugs