Annotation Detail

Information
Associated Genes
CFH
Associated Variants
CFH MUTATION
CFH MUTATION
Associated Disease
Meningococcal Infections
Source Database
DisGeNET
Description
The CFH-CFHR3-CFHR1 aHUS-risk haplotype seems to be the same as was previously associated with protection against meningococcal infections, suggesting that the genetic variability in this region is limited to a few extended haplotypes, each with opposite effects in various human diseases.
Pubmed
26163426
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD
DisGENET score for the Gene Disease association
0.124267125083164
Drugs