Annotation Detail

Information
Associated Genes
FTO
Associated Variants
FTO c.46-40478T>A ( ENST00000637969.1, ENST00000637001.1, ENST00000471389.6, ENST00000636491.1, ENST00000636218.1 )
FTO c.46-23525T>A ( ENST00000636491.1, ENST00000636218.1, ENST00000471389.6, ENST00000637969.1, ENST00000637001.1 )
FTO c.46-40478T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
FTO c.46-23525T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
Associated Disease
Overweight
Source Database
DisGeNET
Description
We genotyped FTO variants rs1558902 and rs9939609 and measured insulin resistance in fasting plasma samples at baseline and at 6-mo and 2-y visits in 743 overweight or obese adults (aged 30-70 y, 60% women) from a randomized weight-loss dietary interventional trial, the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial.
Pubmed
25761503
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0130728171215728
Year of publication
2015
Drugs