Annotation Detail
Information
- Associated Genes
- MEN1
- Associated Variants
-
MEN1 MUTATION
MEN1 MUTATION - Associated Disease
- multiple endocrine neoplasia type 1
- Source Database
- DisGeNET
- Description
- To examine the in vivo function of menin in bone, we conditionally inactivated Men1 in mature osteoblasts by crossing osteocalcin (OC)-Cre mice with floxed Men1 (Men1(f/f)) mice to generate mice lacking menin in differentiating osteoblasts (OC-Cre;Men1(f/f) mice).
- Pubmed
- 25538250
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree,CLINVAR,CTD_human,GAD,LHGDN,MGD,ORPHANET,UNIPROT
- DisGENET score for the Gene Disease association
- 0.687063011914947
Drugs