Annotation Detail
Information
- Associated Genes
- IL10
- Associated Variants
-
rs4252243
IL10RA p.Ala153= (p.A153=) ( ENST00000227752.8 )
IL10RA p.Pro175= (p.P175=) ( ENST00000227752.8 )
IL10 c.378+19T>C ( ENST00000664374.2, ENST00000659065.2, ENST00000471071.2, ENST00000656872.2, ENST00000659997.3, ENST00000659642.2, ENST00000423557.1 )
IL10 c.225+56A>G ( ENST00000656872.2, ENST00000659997.3, ENST00000659642.2, ENST00000423557.1, ENST00000664374.2, ENST00000659065.2 )
IFNAR2-IL10RB c.710-2668C>T ( ENST00000433395.7 )
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E) ( ENST00000290200.7, ENST00000609556.3, ENST00000637650.2, ENST00000433395.7 )
rs4252243
IL10RA p.Ala153= (p.A153=) ( ENST00000227752.8 )
IL10RA p.Pro175= (p.P175=) ( ENST00000227752.8 )
IL10 c.378+19T>C ( ENST00000423557.1, ENST00000471071.2, ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IL10 c.225+56A>G ( ENST00000423557.1, ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
IFNAR2-IL10RB c.710-2668C>T ( ENST00000433395.7 )
IFNAR2-IL10RB p.Lys267Glu (p.K267E), IL10RB p.Lys47Glu (p.K47E) ( ENST00000290200.7, ENST00000609556.3, ENST00000637650.2, ENST00000433395.7 ) - Associated Disease
- Ischemic stroke
- Source Database
- DisGeNET
- Description
- To investigate whether IL10, IL10RA, and IL10RB polymorphisms are associated with the risk of ischemic stroke (IS), selected two IL10 SNPs (rs1518111 and rs1554286), three IL10RA SNPs (rs2256111, rs4252243, and rs2228054), and two IL10RB SNPs (rs999788 and rs2834167) were analyzed in 120 patients with IS and 285 control subjects.
- Pubmed
- 23096091
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00217153497664243
- Year of publication
- 2013
Drugs