Annotation Detail

Information
Associated Genes
ZBTB7C
Associated Variants
ENSG00000284779 c.*1178A>G ( ENST00000416167.7, ENST00000381395.5, ENST00000695541.1, ENST00000381406.8 )
ENSG00000284779 c.*1178A>C ( ENST00000381406.8, ENST00000416167.7, ENST00000381395.5, ENST00000695541.1 )
ADIPOQ c.214+62G>T ( ENST00000320741.7, ENST00000444204.2 )
rs2854744
ENSG00000284779 c.*1178A>G ( ENST00000381395.5, ENST00000381406.8, ENST00000416167.7, ENST00000695541.1 )
ENSG00000284779 c.*1178A>C ( ENST00000381395.5, ENST00000381406.8, ENST00000416167.7, ENST00000695541.1 )
ADIPOQ c.214+62G>T ( ENST00000320741.7, ENST00000444204.2 )
rs2854744
Associated Disease
Malignant tumor of colon
Source Database
DisGeNET
Description
We evaluated the association of four insulin-related pathway gene polymorphisms in insulin-like growth factor-1 (IGF-I) (CA)( n ) repeat, insulin-like growth factor-2 (IGF-II) (rs680), insulin-like growth factor-binding protein-3 (IGFBP-3) (rs2854744), and adiponectin (APM1 rs1501299) with colon cancer risk, as well as relationships with circulating IGF-I, IGF-II, IGFBP-3, and C-peptide in a population-based study.
Pubmed
22565227
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2012
Drugs