Annotation Detail

Information
Associated Genes
PIK3R1
Associated Variants
PIK3R1 MUTATION
PIK3R1 MUTATION
Associated Disease
melanoma
Source Database
DisGeNET
Description
Cell division cycle 6, CHEK1, E2F1, EGFR, and PIK3R1 of the module and their relative pathways, cell cycle, and focal adhesion might play important roles of suppression of vemurafenib on melanoma progression.
Pubmed
25983087
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs