Annotation Detail

Information
Associated Genes
TET2
Associated Variants
TET2 MUTATION
TET2 MUTATION
Associated Disease
melanoma
Source Database
DisGeNET
Description
Overexpression of Tet2 in melanoma cells re-established the 5hmC landscape and suppressed cancer progression but inhibiting Tet1 in non-transformed cells did not initiate cellular transformation.
Pubmed
25179374
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GWASCAT
DisGENET score for the Gene Disease association
0.121085767488321
Drugs