Annotation Detail

Information
Associated Genes
UCP2
Associated Variants
UCP2 p.Ala55Val (p.A55V) ( ENST00000663595.2, ENST00000310473.9, ENST00000536983.5 )
UCP3 p.Val56Ala (p.V56A) ( ENST00000314032.9, ENST00000426995.2 )
UCP2 p.Ala55Val (p.A55V) ( ENST00000310473.9, ENST00000536983.5, ENST00000663595.2 )
UCP3 p.Val56Ala (p.V56A) ( ENST00000314032.9, ENST00000426995.2 )
Associated Disease
obesity
Source Database
DisGeNET
Description
In our case-control study we were not able to demonstrate any association between UCP polymorphisms and obesity in T2DM patients; however, in the meta-analysis we detected a significant association of UCP2 -866G/A, Ins/Del, Ala55Val and UCP3 -55C/T polymorphisms with obesity.
Pubmed
24752406
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.222801117254745
Year of publication
2014
Drugs