Annotation Detail
Information
- Associated Genes
- C3
- Associated Variants
-
C3 p.Pro314Leu (p.P314L)
(
ENST00000245907.11 )
C3 p.Pro314Leu (p.P314L) ( ENST00000245907.11 ) - Associated Disease
- Meningitis, Bacterial
- Source Database
- DisGeNET
- Description
- Rs1047286 (Pro314Leu) in complement component 3 was associated with reduced susceptibility to bacterial meningitis after correction for multiple testing: the protective Leu/Leu genotype was found in 5 of 435 patients (1%) compared to 15 of 302 controls (5%; odds ratio [OR] 4.50, 95% confidence interval [CI] 1.62-12.50, p = 0.0017).
- Pubmed
- 23068452
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2013
Drugs