Annotation Detail

Information
Associated Genes
AGTR1
Associated Variants
AGTR1 MUTATION
AGTR1 MUTATION
Associated Disease
Marfan syndrome
Source Database
DisGeNET
Description
Recently, losartan, an angiotensin II type I receptor antagonist (ARB), has shown promising results in a mouse model of MFS and subsequently in humans with MFS and hence is increasingly used.
Pubmed
24527681
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs