Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
IFNGR2 p.Gln83Arg (p.Q83R)
(
ENST00000290219.11,
ENST00000381995.5,
ENST00000405436.5 )
ENSG00000283782 c.-168-15060A>G
IL7R p.Val138Ile (p.V138I) ( ENST00000303115.8, ENST00000506850.5 )
IFNGR2 p.Gln83Arg (p.Q83R) ( ENST00000290219.11, ENST00000381995.5, ENST00000405436.5 )
ENSG00000283782 c.-168-15060A>G
IL7R p.Val138Ile (p.V138I) ( ENST00000303115.8, ENST00000506850.5 ) - Associated Disease
- Lymphoma, Large-Cell, Follicular
- Source Database
- DisGeNET
- Description
- A significant interaction with BMI was only observed for IFNGR2 (rs9808753 P(forinteraction) = .034) and IL7R (rs1494555 P(forinteraction) = .016) for NHL overall; IL7R (rs1494555 P(forinteraction) = .016) and TNF (1799724 P(forinteraction) = .031) for B-cell lymphoma; and IL5 (rs2069812 P(forinteraction) = .034) for T-cell lymphoma.
- Pubmed
- 20952689
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00407162808120455
- Year of publication
- 2011
Drugs