Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Ser649Leu (p.S649L) ( ENST00000355710.8, ENST00000340058.6, ENST00000615310.5, ENST00000713926.1 )
RET p.Tyr791Phe (p.Y791F) ( ENST00000355710.8, ENST00000615310.5, ENST00000340058.6, ENST00000713926.1 )
RET p.Ser649Leu (p.S649L) ( ENST00000340058.6, ENST00000355710.8, ENST00000615310.5, ENST00000713926.1 )
RET p.Tyr791Phe (p.Y791F) ( ENST00000615310.5, ENST00000713926.1, ENST00000340058.6, ENST00000355710.8 )
Associated Disease
Von Hippel-Lindau syndrome
Source Database
DisGeNET
Description
RET p.Tyr791Phe and p.Ser649Leu and VHL p.Pro81Ser are definitely not pathogenic mutations for VHL and MEN 2.
Pubmed
19906784
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0122584915053319
Year of publication
2010
Drugs