Annotation Detail
Information
- Associated Genes
- IL17A
- Associated Variants
-
NC_000006.12:g.52186235G>A
IL17A p.Tyr66Cys (p.Y66C) ( ENST00000648244.1 )
NC_000006.12:g.52186235G>A
IL17A p.Tyr66Cys (p.Y66C) ( ENST00000648244.1 ) - Associated Disease
- Hematologic Neoplasms
- Source Database
- DisGeNET
- Description
- This study retrospectively examined the impact of a single-nucleotide polymorphism (rs2275913, G197A) in the IL-17 gene of a total 510 recipients with hematologic malignancies and their unrelated donors on the clinical outcomes in HLA-matched myeloablative (discovery study) and nonmyeloablative (validation study) BMT through the Japan Marrow Donor Program (JMDP).
- Pubmed
- 21217785
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2011
Drugs