Annotation Detail

Information
Associated Genes
DKK3
Associated Variants
rs1472189 ( ENST00000396505.7 )
DKK2 p.Arg146Leu (p.R146L) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
DKK2 p.Arg146Gln (p.R146Q) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
rs1472189 ( ENST00000396505.7 )
DKK2 p.Arg146Leu (p.R146L) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
DKK2 p.Arg146Gln (p.R146Q) ( ENST00000285311.8, ENST00000510463.1, ENST00000513208.5 )
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
In addition, DKK3 rs1472189 cytosine/thymine (C/T) was associated with distant metastasis, and, DKK2 rs17037102 G-homozygous patients had a decreased risk for death in multivariate Cox regression analysis.
Pubmed
19562778
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2009
Drugs