Annotation Detail
Information
- Associated Genes
- GSTT1
- Associated Variants
-
CYP2E1 c.-117-455C>T
(
ENST00000463117.6 )
GSTZ1 p.Met83Thr (p.M83T) ( ENST00000557053.5, ENST00000349555.7, ENST00000393734.5, ENST00000361389.8, ENST00000216465.10, ENST00000556627.5, ENST00000553586.5, ENST00000554279.5, ENST00000557639.5 )
CYP2E1 c.-117-455C>T ( ENST00000463117.6 )
GSTZ1 p.Met83Thr (p.M83T) ( ENST00000216465.10, ENST00000349555.7, ENST00000361389.8, ENST00000393734.5, ENST00000553586.5, ENST00000554279.5, ENST00000556627.5, ENST00000557053.5, ENST00000557639.5 ) - Associated Disease
- Carcinoma of bladder
- Source Database
- DisGeNET
- Description
- Associations between THMs and bladder cancer were stronger among subjects who were GSTT1 +/+ or +/- versus GSTT1 null (P(interaction) = 0.021), GSTZ1 rs1046428 CT/TT versus CC (P(interaction) = 0.018), or CYP2E1 rs2031920 CC versus CT/TT (P(interaction) = 0.035).
- Pubmed
- 20675267
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0127577679877743
- Year of publication
- 2010
Drugs