Annotation Detail
Information
- Associated Genes
- MET
- Associated Variants
-
MET MUTATION
MET MUTATION - Associated Disease
- Malignant neoplasm of stomach
- Source Database
- DisGeNET
- Description
- Approximately 10 - 20% of gastric cancer presented an increased MET gene copy numbers; inappropriate activation of MET promotes cellular proliferation, cell motility, invasiveness and angiogenesis and is associated with more aggressive phenotype and with a lower survival.
- Pubmed
- 25881479
- Section of the abstract supporting the evidence
- AREAS COVERED
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.012486326115694
Drugs