Annotation Detail
Information
- Associated Genes
- SORT1
- Associated Variants
-
rs662799
LDLR c.*666T>C ( ENST00000252444.10, ENST00000558518.6, ENST00000560467.2 )
APOE p.Arg176Cys (p.R176C) ( ENST00000252486.9 )
CELSR2 c.8055-10A>G ( ENST00000271332.4 )
rs662799
LDLR c.*666T>C ( ENST00000252444.10, ENST00000558518.6, ENST00000560467.2 )
APOE p.Arg176Cys (p.R176C) ( ENST00000252486.9 )
CELSR2 c.8055-10A>G ( ENST00000271332.4 ) - Associated Disease
- coronary artery disease
- Source Database
- DisGeNET
- Description
- CAD association was replicated and/or verified for 4 loci: SORT1 rs611917 (p=1.7 × 10(-8)), APOA5 rs662799 (p=0.0014), LDLR rs1433099 (p=2.1 × 10(-7)), and APOE rs7412 (p=6.1 × 10(-13)).
- Pubmed
- 23050023
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.124810008827325
- Year of publication
- 2012
Drugs